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Methyl-Guard

$46.00
SKU: TH-SF787
UPC: 693749787037
Size: 180 capsules
Manufacturer: Thorne
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Thorne Methyl-Guard - 180 capsules

Methyl-Guard contains betaine, 5-MTHF, methyl-B12, and P5P to support healthy methylation for cardiovascular, cognitive, and bone health. Methylation helps maintain healthy homocysteine levels.

The body's methylation process is key to maintaining a healthy level of homocysteine, as well as to multiple other biochemical processes involving neurotransmitters, detoxification, cardiovascular health, eye health, muscle health, bone health, and redox balance. Maintaining a normal homocysteine level in the blood has joined having normal cholesterol and triglyceride levels as primary objectives for maintaining good cardiovascular health. Because Methyl-Guard promotes healthy methylation, it helps maintain heart, blood vessel, cognitive, nerve, bone, and female reproductive health. Methyl-Guard was the first nutritional supplement on the market to support homocysteine metabolism and healthy methylation using nutrients in their active, tissue-ready forms.

Methylation – the addition of a methyl group (CH3 – one carbon attached to three hydrogens) to another molecule – is an essential and vital biochemical process in the body involved in multiple biochemical pathways involving neurotransmitters, detoxification, cardiovascular health, eye health, muscle health, bone health, and redox balance. A number of specific nutrients are necessary for the process of methylation to occur normally.

Methylation is essential to help maintain a normal level of homocysteine. A deficiency in homocysteine-metabolizing cofactors is commonly seen in the elderly, resulting in an increase in homocysteine levels with advancing age. An elevated homocysteine level associated with aging, as well as low levels of folic acid and vitamins B6 and B12, often results in the decreased methylation of numerous substances, such as DNA and proteins, which in turn decreases the integrity of vascular structures and neurons.* Providing nutritional cofactors for homocysteine metabolism also provides support for a healthy brain.

A number of biochemical imbalances that raise the level of homocysteine can be addressed by supplementing with appropriate nutrient cofactors. For example, folic acid (as L-5-methyltetrahydrofolate), vitamin B12 (as methylcobalamin), and betaine (trimethylglycine) help recycle homocysteine to the amino acid methionine, while the recycling of homocysteine into the beneficial amino acids cysteine and taurine is facilitated by pyridoxal 5'-phosphate (the active form of vitamin B6). Studies have shown these nutrients help maintain a normal level of homocysteine in the blood.

Because homocysteine levels can be higher in individuals in which the enzymatic reaction that converts folic acid to the active methyl donor L-5-methyltetrahydrofolate (5-MTHF) does not function properly, Methyl-Guard contains 400 mcg of active 5-MTHF per capsule.

Take 3 capsules two times daily or as recommended by your health professional. 

Servings per container: 60

 

Three Capsules Contain:
Vitamin B6 (as Pyridoxal 5'-Phosphate) 20.4 mg.
Folate (1.2 mg as L-5-Methyltetrahydrofolate† from L-5-Methyltetrahydrofolic Acid, Glucosamine Salt) 2 mg DFE
Vitamin B12 (as Methylcobalamin) 1.2 mg.
Betaine Anhydrous (Trimethylglycine) 1.8 g.

Other Ingredients: Hypromellose (derived from cellulose) capsule, Silicon Dioxide, Calcium Citrate, Calcium Laurate.

†This product uses Gnosis S.p.A.'s L-5-Methyltetrahydrofolic Acid, Glucosamine Salt (Quatrefolic®). Quatrefolic is a registered trademark of Gnosis S.p.A.

 

ALLERGY WARNING 
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

PREGNANCY 
If pregnant, consult your health professional before using this product.

INTERACTIONS 
5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrent with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity; however, this folate source has not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate.

At Thorne, being able to rely on the safety and efficacy of our nutritional supplement products is the motivating force behind our clinical trials program. Our confidence that each product we formulate and manufacture works in the body comes from extensive clinical research and medical literature that substantiate the presence of each ingredient in each formula.

In addition to confirming the efficacy of our products, clinical research helps us better understand their efficacy. And it paves the way for new discoveries. The ultimate goal of our research partnerships is to help us fulfill our mission of solving the biggest challenges in health and wellness.

At Thorne, we refuse to take short cuts. We have invested in doing comprehensive testing, sourcing the highest quality ingredients, creating a clean manufacturing process, and protecting the environment. Our team of medical professionals, researchers, and engineers lead with science, thoughtfully refining every product and process. That is why we are the brand trusted by healthcare practitioners, U.S. National Teams, and families around the world for more than 30 years.

Thorne cares deeply about where our ingredients come from. We partner only with suppliers whose practices emphasize quality, science, and responsibility. Better ingredients means better potency, absorption, and digestibility - and ultimately better health.